Substrate: ATP-dependent DNA helicase II, 80 kDa subunit (Single stranded DNA-dependent ATP-dependent helicase.)
Seq-ID: P13010 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-48774   NFKB2_HUMAN
MINT-4051792   KU70_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP-dependent DNA helicase activity,
protein C-terminus binding,
telomeric DNA binding,
double-stranded DNA binding,
ATP binding,
promoter binding		 Ku70:Ku80 complex,
nuclear telomere cap complex,
nucleoplasm,
nonhomologous end joining complex		 double-strand break repair via nonhomologous end joining,
provirus integration,
telomere maintenance,
initiation of viral infection
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 577 LKTEQGGAHFSVSSLAEGSVT - 10026262
LTP
1.00
 - -
0.41
 --
S 577 LKTEQGGAHFSVSSLAEGSVT - 15941674
LTP
1.00
 - -
0.41
 --
S 580 EQGGAHFSVSSLAEGSVTSVG - 10026262
LTP
0.17
 - -
0.38
 --
S 580 EQGGAHFSVSSLAEGSVTSVG - 15941674
LTP
0.17
 - -
0.38
 --
T 715 LAPKDKPSGDTAAVFEEGGDV - 10026262
LTP
0.43
 - -
0.50
 --
T 715 LAPKDKPSGDTAAVFEEGGDV - 15941674
LTP
0.43
 - -
0.50
 --

Substrate: ATP-dependent DNA helicase II, 80 kDa subunit (Single stranded DNA-dependent ATP-dependent helicase.)
Seq-ID: P27641 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP-dependent DNA helicase activity,
ATP binding		 Ku70:Ku80 complex,
cytoplasm,
nonhomologous end joining complex		 double-strand break repair via nonhomologous end joining,
negative regulation of apoptosis,
positive regulation of neurogenesis,
hemopoietic stem cell differentiation,
DNA recombination,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 578 YKTEKEEDHISISSLAEGNIT - 10026262
LTP
1.00
 - -
0.44
 - medium
S 581 EKEEDHISISSLAEGNITKVG - 10026262
LTP
0.21
 - -
0.41
 - medium
T 716 LAPKDKAKEDTTGPEEAGDVD - 10026262
LTP
0.07
 - -
0.69
 - medium

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